Coagulation and Bleeding Disorders: Review and Update
نویسندگان
چکیده
منابع مشابه
Coagulation and bleeding disorders: review and update.
Hemostasis is initiated by injury to the vascular wall, leading to the deposition of platelets adhering to components of the subendothelium. Platelet adhesion requires the presence of von Willebrand factor and platelet receptors (IIb/IIIa and Ib/IX). Additional platelets are recruited to the site of injury by release of platelet granular contents, including ADP. The "platelet plug" is stabilize...
متن کاملPostoperative bleeding and coagulation disorders.
PURPOSE OF REVIEW New data have been made available in the field of haemostasis and thrombosis. Some long-awaited answers to important questions have been published, and some debates have benefited from an updated perspective. RECENT FINDINGS Two important domains are addressed in this update: massive bleeding (1/1/1 ratios and fibrinogen concentrates) and the management of direct oral antico...
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Infection, both bacterial and nonbacterial, may be associated with coagulation disorders, resulting in disseminated intravascular coagulation and multiorgan failure. In the last few decades a series of in vivo and in vitro studies has provided more insight into the pathogenetic mechanisms and the role of cytokines in these processes. Because of the growing interest in this field, the complexity...
متن کاملEpidemiology of Hereditary Coagulation Bleeding Disorders: A 15-Year Experience From Southern Iran
Background: Data on the frequency of hereditary bleeding disorders (HBDs) and associated mortality and morbidities during a long-term follow-up from Iran are scarce. Objective: This study evaluated the epidemiologic features among patients with HBD in one of the largest referral centers in southern Iran. Methods: In this cross-secti...
متن کاملDetecting coagulation disorders of pregnancy: bleeding time or platelet count?
ry testing has been conducted systematically, assuming that routine coagulation screening would inform clinicians on the hemostatic profile of their patients and help prevent the occurrence of intraoperative hemorrhagic complications. Since 1978 and the article by Eika et al. showing no correlation between the results of preoperative hemostasis testing and intraoperative bleeding complications,...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2000
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/46.8.1260